Loss of NRMT1 allows expression of multiple differentiation pathways and alters transcription of secreted proteins in C2C12 myoblasts
John G. Tooley, Gao Zhou, Jack Forster, Cameron B. Jones, Frank A. Tedeschi, Christine E. Schaner Tooley
This study shows that NRMT1 loss in C2C12 myoblasts disrupts muscle differentiation by altering gene expression related to cell cycle, muscle specification, and other lineage pathways.
bioRxiv · Jul 29, 2025 · PreprintGenomics