Gao Zhou

This study investigates how cardiac arrest affects myocardial ribosome biology and protein synthesis in pigs and mice, finding increased ribosomal transcripts with ischemic burden and suppressed ribosome activity post-arrest.

This study identifies Hog1/p38 and ZAKα as drivers of Shwachman-Diamond syndrome and shows their inhibition can restore cell growth in SDS models.

This paper identifies a cytoplasmic role for NRMT1 in regulating translation by interacting with ribosomal subunits and affecting mRNA selection in C2C12 mouse myoblasts.

This study shows that NRMT1 loss in C2C12 myoblasts disrupts muscle differentiation by altering gene expression related to cell cycle, muscle specification, and other lineage pathways.

The paper demonstrates that micropatterned human pluripotent stem cells can model early human cardiac vascularization in vitro, resembling a 6.5 post-conception week heart and revealing conserved vascular development programs.

This study shows that eIF6 modulates ribosomal subunit associations, affecting mitotic exit and cancer progression by altering translation efficiency of mitotic factors.

This study identifies eif4e1c's role in zebrafish heart development and regeneration by showing its impact on cardiomyocyte metabolism and proliferation through translation regulation.