Author

John G. Tooley

University at Buffalo, State University of New York

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Christine E. Schaner TooleyiD· 2 shared Frank A. TedeschiiD· 2 shared Gao ZhouiD· 2 shared Arielle Arbel· 1 shared Cameron B. Jones· 1 shared Cameron Jones· 1 shared Jack Forster· 1 shared Sarah Obeidat· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

Christine E. Schaner TooleyORCID

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2 papers

Recent·Most cited

Characterization of novel cytoplasmic roles for the N-terminal methyltransferase NRMT1

John G. Tooley, Gao Zhou, Sarah Obeidat, Arielle Arbel, Cameron Jones, Frank A. Tedeschi, Christine E. Schaner Tooley

This paper identifies a cytoplasmic role for NRMT1 in regulating translation by interacting with ribosomal subunits and affecting mRNA selection in C2C12 mouse myoblasts.

bioRxiv · Jan 18, 2026 · PreprintBiochemistry

Loss of NRMT1 allows expression of multiple differentiation pathways and alters transcription of secreted proteins in C2C12 myoblasts

John G. Tooley, Gao Zhou, Jack Forster, Cameron B. Jones, Frank A. Tedeschi, Christine E. Schaner Tooley

This study shows that NRMT1 loss in C2C12 myoblasts disrupts muscle differentiation by altering gene expression related to cell cycle, muscle specification, and other lineage pathways.

bioRxiv · Jul 29, 2025 · PreprintGenomics