Cellular Context Influences Kinase Inhibitor Selectivity
M. Binder, Frances M. Bashore, Kaitlin K. Dunn Hoffman, Cameron Damgaard, Michael R. Slater, David Harold Drewry, Matthew B. Robers, Alison Donnelly Axtman
The paper compares cell-free and cellular assays for kinase inhibitor selectivity, finding divergent results and identifying new kinase interactions in cells.
Journal of Medicinal Chemistry · Feb 6, 2026Peer-reviewedCell Biology