Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid dependence
Olivia Corradin, Richard C. Sallari, An T. Hoang, Bibi S. Kassim, Gabriella Ben Hutta, Lizette Cuoto, Bryan C. Quach, Katreya Lovrenert, Cameron Hays, Berkley E. Gryder, Marina Iskhakova, Hannah M. Cates, Yanwei Song, Cynthia F. Bartels, Dana B. Hancock, , Peter C. Scacheri
The paper identifies case-specific epigenetic alterations in opioid dependence using ChIP-seq and Hi-C, revealing convergent regulatory loci associated with genetic and environmental risk factors.
bioRxiv · Jun 15, 2021 · PreprintGenomics