Efficient and specific Ly6G+ cell depletion: A change in the current practices toward more relevant functional analyses of neutrophils
Julien Faget, Gael Boivin, Pierre-Benoit Ancey, Aspasia Gkasti, Julie Mussard, Camilla Engblom, Christina Pfirschke, Jessica Vazquez, Nathalie Bendriss-Vermare, Christophe Caux, Marie-Catherine Vozenin, Mikael J. Pittet, Matthias Gunzer, Etienne Meylan
The paper compares anti-Gr1 and anti-Ly6G antibodies for neutrophil depletion, showing anti-Ly6G's inefficacy in C57BL/6 mice but its potential for specific depletion when combined with a secondary antibody.
bioRxiv · Dec 18, 2018 · PreprintImmunology