Proof-of-principle of NF1 Gene Therapy in plexiform neurofibroma mice models
Dhanushka Hewa Bostanthirige, Camille Plante, Molly A. Caron, Suzanne Gascon, Maude Lévesque, Colin Poirier, Mathieu Deschênes, Jean-Paul Sabo Vatasescu, Benoı̂t Chabot, Sameh Geha, Benoît Laurent, Jean‐Philippe Brosseau
This study demonstrates that restoring NF1 gene expression in established neurofibromas can lead to tumor regression in mouse models.
Communications Biology · Feb 12, 2026Peer-reviewedCancer Biology