Benoı̂t Chabot

This study demonstrates that restoring NF1 gene expression in established neurofibromas can lead to tumor regression in mouse models.

This paper identifies 5342191 as a broad-spectrum antiviral that inhibits HIV-1, adenovirus, coronavirus, and influenza by altering viral RNA accumulation and structural protein expression.

This study identifies DYRK1A as a kinase that interacts with HBV cccDNA and enhances HBV RNA production by regulating the enhancer 1/X promoter.

The paper shows that transient RNPS1 depletion causes perdurable changes in alternative splicing for RNPS1-regulated events, suggesting a role for splicing regulators in shaping transcript diversity.