Shifting Perspectives on Biotherapeutic Treatment in Ulcerative Colitis using Lipid Mesophases: Formulation Design and Preclinical Validation
Rafaela Pletsch Gazzi, Cremona Tiziana, Czekalla Reto, Campbell Emily, Marlene Schwarzfischer, Gerhard Rogler, Scharl Michael, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri
This study develops and validates a localized delivery system for infliximab in ulcerative colitis, showing improved therapeutic efficacy and reduced systemic absorption.
bioRxiv · Feb 10, 2026 · PreprintPathology