Combinatorial screening of nanoparticles for nose-to-brain RNA delivery to modulate neuroinflammation after traumatic brain injury
Yihan Xing, Vy Do, Zunkai Xu, Clara Do, Canyuan Yang, Ziyue Zhu, Jingjing Gao
The paper screens lipid nanoparticles for intranasal RNA delivery to reduce neuroinflammation after traumatic brain injury, identifying effective candidates that lower microRNA-9-5p and improve outcomes.
bioRxiv · May 30, 2026 · PreprintBioengineering