Author

Carina Jägers

University of California, Berkeley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Henk RoelinkiD· 2 shared

Activity by Year

2019-2020 · peak 1/yr

2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 10, 2020

Non-cell autonomous inhibition of the Shh pathway due to impaired cholesterol biosynthesis requires Ptch1/2

Carina Jägers, Henk Roelink

The paper shows that mutations in cholesterol synthesis genes impair Shh signaling in neighboring cells via Ptch1/2 efflux of cholesterol precursors.

DOI 10.1101/2020.12.10.420588

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintDec 17, 2019

Association of Sonic Hedgehog with the Extracellular Matrix Requires its Putative Zinc-Peptidase Activity

Carina Jägers, Henk Roelink

This study shows that Sonic Hedgehog's zinc-coordination fold is necessary for its association with the extracellular matrix and non-cell autonomous signaling.

1 citation

statistical model

𝕏 PostBluesky