Dynamic TET1 repression coordinates activation of macroH2A.2-poised bivalent genes during neuroectoderm differentiation
Brendan Terry, Carine Stapel, Fátima Santos, Joshua Kent, Kamal Kishore, Clive S. D’Santos, Ian Chambers, Aled Parry, Wolf Reik
The paper identifies a non-catalytic repressor function of TET1 and an activating role of macroH2A.2 in bivalent chromatin during neuroectoderm differentiation.
bioRxiv · Oct 19, 2026 · PreprintDevelopmental Biology