Kamal Kishore

Temporal phosphoproteomic programmes set a redox-gated rheostat on neutrophil phagocytosis

This paper identifies a redox-gated phagocytic rheostat in neutrophils by analyzing phosphoproteomic and functional responses to bacterial exposure.

Dynamic TET1 repression coordinates activation of macroH2A.2-poised bivalent genes during neuroectoderm differentiation

The paper identifies a non-catalytic repressor function of TET1 and an activating role of macroH2A.2 in bivalent chromatin during neuroectoderm differentiation.

IL-1-activated cancer-associated fibroblasts promote STAT1-driven transcriptional reprogramming of pancreatic tumour cells

This paper shows that IL-1-activated cancer-associated fibroblasts (iCAFs) promote STAT1-driven transcriptional reprogramming in pancreatic tumour cells, leading to chemoresistance and identifying STAT1 as a therapeutic target.

EstroGene2.0: A multi-omic database of response to estrogens, ER-modulators, and resistance to endocrine therapies in breast cancer

EstroGene2.0 is a multi-omic database that compiles data on estrogen receptor responses and resistance in breast cancer, revealing diverse transcriptomic changes and identifying key targets.

Multi-omics analysis demonstrates a critical role for GLP methyltransferase in transcriptional repression during oogenesis

The paper investigates the role of GLP methyltransferase in oocyte development using multi-omics analysis and mouse models, finding that GLP contributes to transcriptional repression and is critical for oogenesis.

The distinct effects of MEK and GSK3 inhibition upon the methylome and transcriptome of mouse embryonic stem cells

The paper examines how MEK and GSK3 inhibition affects the methylome and transcriptome of mouse embryonic stem cells, revealing distinct epigenetic and transcriptional changes.

DNA methylation dynamics during embryonic development and postnatal maturation of the mouse auditory organ of Corti

The paper analyzes DNA methylation dynamics in the mouse auditory organ of Corti during development and maturation, identifying novel regulatory regions and candidate factors involved in inner ear development.