Hair follicle stem cell fate supports distinct clinical endotypes in Hidradenitis Suppurativa
Audrey Onfroy, Francette Jean‐Louis, Philippe Le Corvoisier, Fanny Coulpier, Kévin Muret, Éric Bonnet, Raphaele Arrouasse, Caroline Boucle, Salwa Abid, É. Sbidian, Christina Bergqvist, P. Wolkenstein, Véronique Godot, Jean‐François Deleuze, Yves Lévy, , Sophie Hüe
This study uses single-cell RNA sequencing to identify distinct HF stem cell differentiation trajectories in HS patients, linking them to three clinical endotypes defined by inflammation, keratinization, and mixed features.
Journal of the European Academy of Dermatology and Venereology · Nov 6, 2025Peer-reviewedImmunology