Audrey Onfroy

This study benchmarks bioinformatics methods for single-cell and spatial RNA-seq Nanopore long-read data, evaluating their accuracy, robustness, and scalability across different protocols and sequencing conditions.

This study uses single-cell RNA sequencing to identify distinct HF stem cell differentiation trajectories in HS patients, linking them to three clinical endotypes defined by inflammation, keratinization, and mixed features.

This study uses a Nf1-KO mouse model to investigate the initiation of plexiform neurofibromas, finding that skin trauma accelerates tumor development and that Nf1 heterozygosity contributes to mutant Schwann cell expansion.