Robust and scalable single-molecule protein sequencing with fluorosequencing
James Mapes, Julia Stover, Heather D. Stout, Tucker M. Folsom, Emily Babcock, Sandra Loudwig, Christopher Martin, Mariah J. Austin, Fan Tu, Casey J. Howdieshell, Zachary Booth Simpson, Thomas Blom, Daniel C. Weaver, Daniel Winkler, Kent Vander Velden, , Jagannath Swaminathan
This paper improves fluorosequencing by optimizing fluorophores, reducing dye interactions, and creating an end-to-end workflow, demonstrating its potential for high-sensitivity clinical proteomics.
bioRxiv · Sep 15, 2023 · PreprintMolecular Biology