{Phi}X174 bacteriophage viability predicted by protein biophysical modeling
James T. Van Leuven, Jagdish Suresh Patel, Casey M. Beard, Frederick Marty Ytreberg, LuAnn Scott, Kellee Burns, Emma R. Altman, Yesol Sapozhnikov, Chénangnon Frédéric Tovissodé, Jordan Yang, Holly A. Wichman, Brenda M. Rubenstein, Craig R. Miller
The paper evaluates predictive models for {Phi}X174 bacteriophage viability using biophysical and molecular modeling approaches, finding that large-effect mutations are highly informative for predicting phenotypes.
bioRxiv · Dec 2, 2025 · PreprintMolecular Biology