Protein Kinases MpkA and SepH Transduce Crosstalk Between CWI and SIN Pathways to Activate Protective Hyphal Septation Under Echinocandin Cell Wall Stress
Alexander G. Doan, Jessica E. Schafer, Casey M. Douglas, Matthew S. Quintanilla, Meredith E. Morse, Harley Edwards, Walker D. Huso, Kelsey Gray, JungHun Lee, Joshua K. Dayie, Steven D. Harris, Mark R. Marten
This study identifies crosstalk between the CWI and SIN pathways in fungi, showing that it enables hyperseptation under echinocandin stress, which contributes to resistance.
mSphere · Dec 13, 2024Peer-reviewedMicrobiology