Investigating the Role and Regulation of GPNMB in Progranulin-deficient Macrophages
Drew A. Gillett, Noelle K. Neighbarger, Cassandra Cole, Rebecca L. Wallings, Malú Gámez Tansey
This study investigates GPNMB upregulation and MITF dysregulation in progranulin-deficient macrophages, linking them to early-stage neurodegenerative disease mechanisms.
bioRxiv · Mar 12, 2024Immunology