Author

Drew A. Gillett

University of Florida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Hannah A. StaleyiD· 2 shared Holly B. KordasiewicziD· 2 shared Malú G. TanseyiD· 2 shared Noelle K. NeighbargeriD· 2 shared Rebecca L. WallingsiD· 2 shared Warren D. HirstiD· 2 shared Julian Mark· 1 shared Julian R MarkiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 34 mutual co-author links

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2 shared papersImmunology

Hannah A. StaleyORCID

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2 papers

Recent·Most cited

ASO-mediated knockdown of GPNMB in mutant-GRN and Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses

Rebecca L. Wallings, Drew A. Gillett, Hannah A. Staley, Savanna Mahn, Julian Mark, Noelle K. Neighbarger, Holly B. Kordasiewicz, Warren D. Hirst, Malú G. Tansey

This study shows that reducing GPNMB in progranulin-deficient myeloid cells impairs lysosomal function and immune responses, suggesting GPNMB is essential for maintaining immune homeostasis.

Molecular Neurodegeneration · Apr 8, 2025Peer-reviewedImmunology

Totally tubular: ASO-mediated knock-down of G2019S-Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages

Rebecca L. Wallings, Julian R Mark, Hannah A. Staley, Drew A. Gillett, Noelle K. Neighbarger, Holly B. Kordasiewicz, Warren D. Hirst, Malú G. Tansey

This study shows that reducing mutant Lrrk2 in macrophages decreases lysosomal tubule formation and pro-inflammatory responses, suggesting potential therapeutic benefits for LRRK2-related Parkinson's but possible immune system side effects.

bioRxiv · Jul 14, 2023 · PreprintNeuroscience