The gut microbiome promotes detoxification responses to an environmental toxicant
Ian N Krout, Rie Matsuzaki, Alexandria C. White, Sherry Tsui, Lisa Blackmer‐Raynolds, Sean D. Kelly, Jianjun Chang, Mattie Braselton, Priya E D'Souza, Catherine E. Mullins, Parinya Panuwet, Volha Yakimavets, Dana Boyd Barr, Douglas Ian Walker, William Michael Caudle, Timothy Robert Sampson
This study shows the gut microbiome is necessary for host detoxification responses to deltamethrin, with both developmental and active microbial signaling contributing to hepatic and colonic detoxification.
bioRxiv · Aug 14, 2025 · PreprintPharmacology & Toxicology