Vsb1, Ypq1 and Ypq2 control dynamic cationic amino acid storage in the yeast vacuole
Evi Zaremba, Fabienne Vierendeels, Raphaël Dutoit, Elisabeth Bodo, Ersilia Bifulco, Catherine Tricot, Εlad Noor, Bruno André, Evgeny A. Onischenko, Melody Cools
Zaremba et al. characterize Vsb1 as the main yeast vacuolar lysine importer and Ypq1/2 as bidirectional vacuolar transporters of lysine and arginine. Their study highlights the role of vacuolar transporters in regulating cationic amino acid homeostasis under fluctuating nutrient availability.
Life Science Alliance · Apr 28, 2026Peer-reviewedCell Biology