Intracellular C. neoformans infection stimulates increased glycolytic activity in fetal liver-derived alveolar-like macrophages
Derek A. Wiggins, Josh B. Griggs, Andrew England, Emily N. Callison, Cedra H. Kamel, Cathrine A. Hasan, A. Todd Davis, Morgan E. Chappell, Kayla N. Conner, Andrew J. Olive, Erin E. McClelland, Rachel N. Leander, Rebecca L. Seipelt-Thiemann, David E. Nelson
This study shows that C. neoformans infection increases glycolytic activity in fetal liver-derived alveolar-like macrophages, which is HIF1-dependent.
bioRxiv · Nov 28, 2025 · PreprintImmunology