Developmentally programmed nuclear pore complex replacement enables oocyte specification
Shruti Venkat, Tram Nguyen, Cecilia Blangini, Michelle Pollak, Karen Schindler, Maya Capelson, Prashanth Rangan
The paper identifies a developmentally programmed nuclear pore complex (NPC) turnover pathway during oocyte specification in Drosophila, showing that NPC renewal is essential for proper oocyte identity and maternal provisioning.
bioRxiv · Feb 16, 2026 · PreprintDevelopmental Biology