Prashanth Rangan

The paper identifies a tumor-promoting role of Nup93-2 in Drosophila, showing its specific effect on gene silencing and JAK/STAT signaling through Polycomb domains.

The paper identifies a developmentally programmed nuclear pore complex (NPC) turnover pathway during oocyte specification in Drosophila, showing that NPC renewal is essential for proper oocyte identity and maternal provisioning.

The paper identifies a mechanism where TORC1-driven translation of Nup44A promotes chromatin remodeling and facilitates the germ cell-to-maternal transition in Drosophila.

The paper shows that genome organization influences NPC formation and differentiation in Drosophila oogenesis by regulating gene silencing and Nup activation.

The paper investigates the role of Msl3 in meiotic entry in mice and finds that its loss-of-function does not disrupt spermatogenesis.

The paper shows that pseudouridylation of rRNA is required for ribosome biogenesis and oocyte specification in Drosophila, with effects on translation of polyglutamine proteins during differentiation.

Oo-site visualizes gene expression and translational data during Drosophila oogenesis, revealing meiotic genes are regulated post-transcriptionally.

This study identifies MSL3 as a master regulator coordinating transcription and translation during meiosis in female Drosophila and shows its conserved role in mouse spermatogenesis.

The paper identifies RNA degradation mechanisms during Drosophila oogenesis that sculpt the maternal transcriptome by removing specific RNAs expressed in germline stem cells.

The paper identifies a translation control module involving RNA helicases that links ribosome biogenesis to germline stem cell differentiation in Drosophila.

The paper shows that transcriptional interference at the endogenous Adh locus in Drosophila melanogaster is developmentally regulated and tunable through distal promoter activity.

The paper identifies a conserved 10-nucleotide sequence in maternal mRNAs that is bound by different RNA-binding proteins at different stages of oogenesis to regulate translation.