A critical role for the anterior insula in impaired adult social interaction after early life maltreatment.
Matthew Gene Kearney, Zoe G. Beatty, Miranda R. Mayeaux, Zephyr Wang, Oluwarotimi O. Folorunso, Celia Middleton, Emily L. Newman, William A. Carlezon, James McNally, Kerry James Ressler, Erin E. Hisey
This study identifies the anterior insula as a key circuit affected by early life maltreatment, showing its role in male social avoidance in adulthood.
bioRxiv · Jun 3, 2026 · PreprintNeuroscience