Author

Celine Leppert

New York Medical College

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Molecular Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Joseph D. Etlinger· 1 shared Malik BisserieriD· 1 shared Marîa Teresa OchoaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperMolecular Biology

Joseph D. Etlinger

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1 paper

Recent·Most cited

Epigenetic Activation of Endothelial Smurf1 via EP300-Mediated H3K27ac Disrupts BMPR2 Signaling in Pulmonary Arterial Hypertension

Celine Leppert, Marîa Teresa Ochoa, Joseph D. Etlinger, Malik Bisserier

This study identifies epigenetic activation of Smurf1 via EP300-mediated H3K27ac as a driver of BMPR2 signaling disruption in PAH, showing therapeutic potential through Smurf1 inhibition.

bioRxiv · Oct 30, 2025 · PreprintMolecular Biology