Author

Marîa Teresa Ochoa

New York Medical CollegeORCID 0000-0001-6550-5008Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Malik BisserieriD· 3 shared Anurupa GhoshiD· 2 shared Katherine JankowskiiD· 2 shared Lahouaria HadriiD· 2 shared Anjira S. Ambade· 1 shared Carlos G. Santos‐GallegoiD· 1 shared Celine Leppert· 1 shared Gregory DavidiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMolecular Biology

Malik BisserierORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 2, 2026

Targeting IL-6-STAT3/STAT4 Signaling Restores FOXP3 Expression in Pulmonary Arterial Endothelium and Reveals Novel Biomarkers for PAH

Prabhjot Kaur, Katherine Jankowski, Anurupa Ghosh…·Lahouaria Hadri

This study shows that blocking IL-6 restores FOXP3 expression in PAH, revealing its role as a biomarker and therapeutic target.

DOI 10.64898/2026.04.29.721729

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Molecular BiologybioRxivPreprintFeb 3, 2026

Sotatercept Reverses SIN3a Deficiency-Driven PAH by Reprogramming BMPR2/TGF-β-HIF-1α Signaling Pathways

Katherine Jankowski, Anurupa Ghosh, Marîa Teresa Ochoa…·Lahouaria Hadri

This study shows that Sotatercept reverses SIN3a deficiency-driven pulmonary arterial hypertension by reprogramming BMPR2/TGF-β-HIF-1α signaling pathways.

1 citation

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintOct 30, 2025

Epigenetic Activation of Endothelial Smurf1 via EP300-Mediated H3K27ac Disrupts BMPR2 Signaling in Pulmonary Arterial Hypertension

Celine Leppert, Marîa Teresa Ochoa, Joseph D. Etlinger, Malik Bisserier

This study identifies epigenetic activation of Smurf1 via EP300-mediated H3K27ac as a driver of BMPR2 signaling disruption in PAH, showing therapeutic potential through Smurf1 inhibition.

1 citation

humanbulk RNA-seq

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