Cesar Augusto Vargas-Garcia

The paper models cell size homeostasis using stochastic hybrid systems and shows that different regulatory strategies can achieve bounded size variation.

The paper develops a first-passage time model to explain bacterial cell-division timing, showing that added volume between divisions is size-independent and noise increases with birth size.

The paper derives analytical formulas to decompose protein level variability into components from stochastic expression, partitioning errors, and cell-division timing, and shows how genome duplication timing affects noise.