Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells
Syed Faaiz Enam, Sajidur Rahman Kader, Nicholas Bodkin, Johnathan G. Lyon, Mark A. Calhoun, Cesar Azrak, Pooja Munnilal Tiwari, Daryll A. Vanover, Haichen Wang, Philip J. Santangelo, Ravi V. Bellamkonda
This study evaluates the effect of transient IL-4 expression from engineered MSCs on M2-like macrophage enrichment after TBI, finding no improvement in functional or histological outcomes.
Journal of Neuroinflammation · Jun 20, 2020Peer-reviewedNeuroscience