cDNA-guided functional selection uncovers selective defense systems against RNA phages
Hee‐Won Bae, Hyeong-Joon Ki, Shin-Yae Choi, Han-Gyu Cho, Chae-Hyeon Woo, M. A. Kim, Hyung-Jun CHUN, You‐Hee Cho
This paper uses a cDNA-based functional selection strategy to identify RNA phage defense systems in Pseudomonas aeruginosa, uncovering new defense mechanisms and characterizing ZwsA as an RNA endonuclease.
bioRxiv · Apr 7, 2026 · PreprintMicrobiology