Author

Chak-Ho Li

Chinese University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Allen E. J. Yoeh· 1 shared Amita TrehaniD· 1 shared Chase C. SuiteriD· 1 shared Chi Kong LiiD· 1 shared Chris Parish· 1 shared Colton J. SmithiD· 1 shared Deepa BhojwaniiD· 1 shared Douglas M. FowleriD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Allen E. J. Yoeh

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1 paper

Recent·Most cited

Massive parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity

Chase C. Suiter, Takaya Moriyama, Kenneth A. Matreyek, Wentao Yang, Emma Rose Scaletti, Rina Nishii, Wenjian Yang, Keito Hoshitsuki, Minu Singh, Amita Trehan, Chris Parish, Colton J. Smith, Deepa Bhojwani, Liz Y. P. Yuen, Chi Kong Li, , Jun J.J. Yang

The paper identifies 1,103 deleterious NUDT15 variants using functional assays, improving pharmacogenetics-guided thiopurine treatment by accurately predicting toxicity risk alleles.

bioRxiv · Aug 20, 2019 · PreprintGenomics