Author

Chang Ying

Second Affiliated Hospital of Zhejiang University

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Chengmeng Jin· 1 shared Di WangiD· 1 shared Hao WuiD· 1 shared Minfeng YingiD· 1 shared Siying Zeng· 1 shared Xun HuiD· 1 shared Yuqi WangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Chengmeng Jin

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1 paper

Recent·Most cited

Elucidating the kinetic and thermodynamic insight into regulation of glycolysis by lactate dehydrogenase and its impact on tricarboxylic acid cycle and oxidative phosphorylation in cancer cells

Siying Zeng, Yuqi Wang, Minfeng Ying, Chengmeng Jin, Chang Ying, Di Wang, Hao Wu, Xun Hu

This study investigates how lactate dehydrogenase (LDH) regulates glycolysis, TCA cycle, and oxidative phosphorylation in cancer cells through kinetic and thermodynamic mechanisms, showing that LDH inhibition disrupts metabolic pathways and induces cell death under hypoxia.

bioRxiv · Jun 26, 2024 · PreprintBiochemistry