Author

Hao Wu

Second Affiliated Hospital of Zhejiang UniversityORCID 0000-0002-1035-6567Unclaimed ORCID profile · follow to get notified of new preprints

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Hao Wu23 papers · University of Pennsylvania

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Chang Ying· 1 shared Chengmeng Jin· 1 shared Di WangiD· 1 shared Minfeng YingiD· 1 shared Siying Zeng· 1 shared Xun HuiD· 1 shared Yuqi WangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Chang Ying

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1 paper

Recent·Most cited

Elucidating the kinetic and thermodynamic insight into regulation of glycolysis by lactate dehydrogenase and its impact on tricarboxylic acid cycle and oxidative phosphorylation in cancer cells

Siying Zeng, Yuqi Wang, Minfeng Ying, Chengmeng Jin, Chang Ying, Di Wang, Hao Wu, Xun Hu

This study investigates how lactate dehydrogenase (LDH) regulates glycolysis, TCA cycle, and oxidative phosphorylation in cancer cells through kinetic and thermodynamic mechanisms, showing that LDH inhibition disrupts metabolic pathways and induces cell death under hypoxia.

bioRxiv · Jun 26, 2024 · PreprintBiochemistry