Synaptic engram underlies memory
Dae Hee Han, Hoonwon Lee, Jongrok Do, Pojeong Park, Hyunmin Park, Hyungji Lee, Y. K. Kim, Chang-Ho Kim, JooYoung Kim, Chaery Lee, Jun-Yeong Baek, Myunghyun Cheon, Ji‐il Kim, Dong Il Choi, Doyun Lee, Bong‐Kiun Kaang
The paper shows that synaptic depression between memory-encoding engram cells impairs memory, demonstrating that synaptic plasticity between these cells causally supports memory.
bioRxiv · Jul 31, 2026 · PreprintNeuroscience