The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis
Meiai He, Lining Liang, Yulu Wang, Yongyu Chen, Han Sun, Lin Guo, Changpeng Li, Jingcai He, Yanhua Wu, Shiyu Chen, Tingting Yang, Fei Meng, Qiwen Ren, Linna Dong, Lin Liu, , Hui Zheng
This study shows that the Par complex regulates cell polarity and differentiation by modulating FAK signaling through the AKT-FURIN-LEFTY pathway in mouse embryonic stem cells.
bioRxiv · Oct 2, 2026 · PreprintDevelopmental Biology