Han Sun

The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis

This study shows that the Par complex regulates cell polarity and differentiation by modulating FAK signaling through the AKT-FURIN-LEFTY pathway in mouse embryonic stem cells.

Atomic structure and plasticity of the MthK-CTX complex investigated by cryo-EM, NMR, and MD simulations

The paper investigates the binding of scorpion toxin CTX to the MthK channel using cryo-EM, NMR, and MD simulations to explain toxin affinity and subtype tolerance.

Ultraflexible Ion-Specific Nanoelectrodes for Long-Term Potassium Monitoring in Plants

This paper introduces PINE arrays for long-term, ultraflexible potassium monitoring in plants, enabling continuous tracking of ion dynamics without disrupting cellular structure.

Canalized gene regulatory networks stabilize floral polymorphism and enable modular transgressive expression

The paper investigates how canalized gene regulatory networks maintain floral polymorphism in Stellera chamaejasme by analyzing transcriptomic and regulatory variation across morphs.

Atomic structure and dynamics of the mechanosensitive channel MscL from E. coli by cryo-EM and solid-state NMR

This study uses cryo-EM and solid-state NMR to determine the structure and dynamics of MscL from E. coli, revealing lipid-protein interactions that drive mechanosensitive gating.