The thermotolerant Arabian killifish, Aphanius dispar, as a novel infection model for human fungal pathogens
Rashid Minhas, Tina Bedekovic, Teigan Veale, Larissa L.H. John, Atyaf Saied Hamied, Elliott Scrase, Sienna Read, Chantelle Davies, Hugh Gifford, Rhys A. Farrer, Steven Bates, Alexandra Brand, Mark Ramsdale, Tetsuhiro Kudoh
This study introduces the thermotolerant Arabian killifish as a new model to assess C. albicans virulence at human-relevant temperatures, showing temperature-dependent virulence and drug response.
bioRxiv · Oct 8, 2024 · PreprintAnimal Behavior & Cognition