Chao Ren

A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasome

The paper identifies a Pseudomonas aeruginosa VgrG2b fragment cleaved by caspase-11 that inhibits NLRP3 inflammasome activation, promoting infection and improving survival with a specific peptide inhibitor.

Identification And Characterization of Differentially Co-Expressed Head-To-Head Gene Pairs in Pancreatic Cancer

This study identifies differentially co-expressed head-to-head gene pairs in pancreatic cancer and highlights key regulators and potential biomarkers.

iFORM: incorporating Find Occurrence of Regulatory Motifs

iFORM is a tool that improves the accuracy and sensitivity of TF motif scanning by integrating results from multiple motif discovery programs.

Genome-wide identification and characterisation of HOT regions in the human genome

The paper identifies and characterizes HOT regions across human cell types, showing their association with developmental genes and unique epigenetic features.

PEDLA: predicting enhancers with a deep learning-based algorithmic framework

PEDLA uses deep learning to predict enhancers from heterogeneous data, achieving high accuracy across multiple cell types.