ImmunologyeLifePeer-reviewed
A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasome
Yan Qian, Qiannv Liu, Xiangyun Cheng…·Pengyan Xia
The paper identifies a Pseudomonas aeruginosa VgrG2b fragment cleaved by caspase-11 that inhibits NLRP3 inflammasome activation, promoting infection and improving survival with a specific peptide inhibitor.