Intelectin-2 is a broad-spectrum antimicrobial lectin
Amanda E. Dugan, Deepsing Syangtan, Eric B. Nonnecke, Rajeev S. Chorghade, Amanda L. Peiffer, Jenny J. Yao, Jessica Ille-Bunn, Dallis Sergio, Gleb Pishchany, Catherine Dhennezel, Hera C. Vlamakis, Sunhee Bae, Sheila E. Johnson, Chariesse Ellis, Soumi Ghosh, , Laura L. Kiessling
This study identifies intelectin-2 as an antimicrobial lectin that crosslinks mucins and kills microbes by binding glycans in mucus.
Nature Communications · Jan 13, 2026Peer-reviewedMicrobiology