An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans.
Andrew R. McEwan, Benjamin Wen Qing Hing, Johanna Celene Erickson, Greg Hutchings, Charity Urama, Emily Norton-Hughes, Mariam D’Ippolito, Susan Berry, Mirela Delibegović, Felix Graßmann, Alasdair MacKenzie
The paper investigates a polymorphic regulatory region in the BDNF gene associated with obesity and anxiety in mice and humans, showing altered behavior and gene expression.
Molecular Psychiatry · Jan 16, 2024Peer-reviewedGenetics