CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function
Longxin Xie, Jessica Merjane, Cristian A Bergmann, Jiazhen Xu, Shruthi Balasubramaniyan, Bryan T. Hurtle, Charleen T Chu, Christopher J. Donnelly
The paper introduces CUTS, a biosensor for real-time detection of TDP-43 loss-of-function, showing its sensitivity, accuracy, and potential for gene therapy applications.
bioRxiv · Jul 12, 2024 · PreprintMolecular Biology