Author

Charlene Guerin

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 3 Neuroscience· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 6 Organism:mouse· 6 Approach:statistical model· 6 Research Focus:differential expression· 5 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Christine Bôle‐FeysotiD· 6 shared Moı̈se CoëffieriD· 6 shared Adam Tiffay· 4 shared Alexis GoichoniD· 4 shared Candice Lefebvre· 4 shared Charles-Edward Breemeersch· 4 shared Ludovic D. Langlois· 4 shared Pierre DéchelotteiD· 4 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersPathology

Christine Bôle‐FeysotORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Stress limits the beneficial effects of glutamine in male ob/ob mice

Adam Tiffay, Candice Lefebvre, Charles-Edward Breemeersch, Virginie Dreux, Christine Bôle‐Feysot, Charlene Guerin, Elise Maximin, Magali Monnoye, Pierre Déchelotte, Véronique Douard, Alexis Goichon, Moı̈se Coëffier

This study shows that glutamine supplementation improves metabolic and inflammatory parameters in obese mice but loses these benefits under stress conditions.

bioRxiv · Jul 24, 2026 · PreprintPathology

Sex-dependent effects of a glutamine supplementation on metabolic disorders, intestinal barrier function and gut microbiota in mice with diet-induced obesity.

Candice Lefebvre, Adam Tiffay, Charles-Edward Breemeersch, Virginie Dreux, Christine Bôle‐Feysot, Charlene Guerin, Jonathan Breton, Elise Maximin, Magali Monnoye, Pierre Déchelotte, Véronique Douard, Moı̈se Coëffier, Alexis Goichon

This study examines sex-dependent effects of glutamine supplementation on metabolic disorders, intestinal barrier function, and gut microbiota in diet-induced obese mice, finding protective effects in males and harmful effects in females.

Food Research International · Jul 13, 2026Peer-reviewedPathology

Chronic Activity-Based Anorexia triggers a glial response in the hippocampus independent of intestinal epithelial Toll-Like Receptor 4

Léna Rousseau, T. Demangeat, Colin Salaün, Clara Queguiner, Charlene Guerin, Christine Bôle‐Feysot, Oudiaye Maiga, Adam Tiffay, Fatima Léon, Lea Cornaille, David Ribet, Jean-Claude do-Rego, Jean Luc do Rego, Ludovic D. Langlois, Moı̈se Coëffier

This study shows chronic activity-based anorexia causes hippocampal glial changes independent of intestinal TLR4, linking gut microbiota alterations to neuroinflammation.

Journal of Neuroinflammation · May 18, 2026Peer-reviewedNeuroscience

Glutamine alters the response to stress in mice with diet-induced obesity in a sex-dependent manner.

Candice Lefebvre, Adam Tiffay, Charles-Edward Breemeersch, Virginie Dreux, Christine Bôle‐Feysot, Charlene Guerin, Jonathan Breton, Ludovic D. Langlois, Elise Maximin, Magali Monnoye, Pierre Déchelotte, Véronique Douard, Alexis Goichon, Moı̈se Coëffier

This study investigates how glutamine affects stress responses in obese mice, showing sex-dependent differences in glucose tolerance, corticosterone levels, and gut microbiota.

bioRxiv · Nov 21, 2025 · PreprintPathology

Sex-dependent effects of intestinal epithelial TLR4 deletion induced before activity-based anorexia

Colin Salaün, Marion Huré, Charlene Guerin, Christine Bôle‐Feysot, Fatima Léon, Sarah Lenoir, Jean Luc do Rego, Jean-Claude do-Rego, Ludovic D. Langlois, David Ribet, Najate Achamrah, Moı̈se Coëffier

This study investigates the effects of TLR4 deletion in intestinal epithelial cells on intestinal response and energy homeostasis in male and female mice subjected to activity-based anorexia.

bioRxiv · Feb 5, 2025 · PreprintPhysiology

Sex-dependent effects of a high-fat diet on the hypothalamic response in mouse

Virginie Dreux, Candice Lefebvre, Charles-Edward Breemeersch, Colin Salaün, Christine Bôle‐Feysot, Charlene Guerin, Pierre Déchelotte, Alexis Goichon, Moı̈se Coëffier, Ludovic D. Langlois

This study examines sex differences in mouse hypothalamic responses to a high-fat diet, finding sex-specific effects on body weight, neuropeptide expression, and glial activation.

bioRxiv · Sep 10, 2024 · PreprintNeuroscience