Ludovic D. Langlois

Chronic Activity-Based Anorexia triggers a glial response in the hippocampus independent of intestinal epithelial Toll-Like Receptor 4

This study shows chronic activity-based anorexia causes hippocampal glial changes independent of intestinal TLR4, linking gut microbiota alterations to neuroinflammation.

Glutamine alters the response to stress in mice with diet-induced obesity in a sex-dependent manner.

This study investigates how glutamine affects stress responses in obese mice, showing sex-dependent differences in glucose tolerance, corticosterone levels, and gut microbiota.

Sex-dependent effects of intestinal epithelial TLR4 deletion induced before activity-based anorexia

This study investigates the effects of TLR4 deletion in intestinal epithelial cells on intestinal response and energy homeostasis in male and female mice subjected to activity-based anorexia.

Sex-dependent effects of a high-fat diet on the hypothalamic response in mouse

This study examines sex differences in mouse hypothalamic responses to a high-fat diet, finding sex-specific effects on body weight, neuropeptide expression, and glial activation.

AKAP150-anchored PKA regulation of synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the lateral habenula

This study investigates the role of AKAP150 in regulating synaptic transmission, plasticity, and CRF neuromodulation in the lateral habenula using genetic and electrophysiological approaches.

Involvement of Lateral Habenula Dysfunction in Repetitive Mild Traumatic Brain Injury-Induced Motivational Deficits

This study shows that repetitive mTBI causes LHb neuronal dysfunction, leading to motivational deficits, and that inhibiting LHb activity can reverse these deficits.

Blast-induced mild traumatic brain injury alterations of corticotropin-releasing factor neuronal activity in the mouse hypothalamic paraventricular nucleus

This study investigates how blast-induced mild traumatic brain injury (mbTBI) affects corticotropin-releasing factor (CRF) neuronal activity in the mouse hypothalamic paraventricular nucleus (PVN), finding increased firing in dorsal PVN CRF neurons and associated GABAergic synaptic dysfunction.

Potentiation of glutamatergic synaptic transmission onto lateral habenula neurons following early life stress and intravenous morphine self-administration in rats

This study shows that early life stress increases glutamatergic synaptic activity in the lateral habenula, which persists into adulthood and reduces morphine intake and reward behavior in rats.

Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula

This study shows that early life stress alters kappa opioid receptor signaling in the lateral habenula, affecting neuronal excitability and synaptic transmission in rat models.