Christine Bôle‐Feysot

Stress limits the beneficial effects of glutamine in male ob/ob mice

This study shows that glutamine supplementation improves metabolic and inflammatory parameters in obese mice but loses these benefits under stress conditions.

Sex-dependent effects of a glutamine supplementation on metabolic disorders, intestinal barrier function and gut microbiota in mice with diet-induced obesity.

This study examines sex-dependent effects of glutamine supplementation on metabolic disorders, intestinal barrier function, and gut microbiota in diet-induced obese mice, finding protective effects in males and harmful effects in females.

Chronic Activity-Based Anorexia triggers a glial response in the hippocampus independent of intestinal epithelial Toll-Like Receptor 4

This study shows chronic activity-based anorexia causes hippocampal glial changes independent of intestinal TLR4, linking gut microbiota alterations to neuroinflammation.

CLONAL LYMPHOCYTE EXPANSIONS AND JAK-STAT PATHWAY MUTATIONS DEFINE A PATHOGENIC CONTINUUM DRIVING RESISTANCE TO GLUTEN-FREE DIET IN CELIAC DISEASE

This study identifies clonal lymphocyte expansions and JAK-STAT mutations in celiac disease subtypes, revealing shared mechanisms and limitations of JAK inhibitor therapy.

Glutamine alters the response to stress in mice with diet-induced obesity in a sex-dependent manner.

This study investigates how glutamine affects stress responses in obese mice, showing sex-dependent differences in glucose tolerance, corticosterone levels, and gut microbiota.

Sex-dependent effects of intestinal epithelial TLR4 deletion induced before activity-based anorexia

This study investigates the effects of TLR4 deletion in intestinal epithelial cells on intestinal response and energy homeostasis in male and female mice subjected to activity-based anorexia.

Staphylococcus warneri dampens SUMOylation and promotes intestinal inflammation

This study shows that Staphylococcus warneri reduces SUMOylation in intestinal cells, leading to inflammation through its toxin Warnericin RK.

Sex-dependent effects of a high-fat diet on the hypothalamic response in mouse

This study examines sex differences in mouse hypothalamic responses to a high-fat diet, finding sex-specific effects on body weight, neuropeptide expression, and glial activation.

Modeling the critical MCOR-causing deletion in mouse unveils aberrant Sox21 expression in developing and adult iris and ciliary body, and implicates Tgfb2 in MCOR-associated glaucoma and myopia.

The paper models a critical MCOR-causing deletion in mice, revealing aberrant Sox21 expression and implicating Tgfb2 in MCOR-associated glaucoma and myopia.

MINPP1 prevents intracellular accumulation of the cation chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia

This study identifies MINPP1 mutations as a cause of Pontocerebellar Hypoplasia, showing that MINPP1 deficiency leads to IP6 accumulation and cation chelation, disrupting brain development.