Actin and Src-family kinases regulate nuclear YAP1 and its export
Nil Ege, Anna M. Dowbaj, Ming Jiang, Michael T. Howell, Steven Hooper, Charles Foster, Robert P. Jenkins, Erik A. Sahai
This study identifies mechanisms regulating YAP1 nuclear shuttling in fibroblasts, showing that Src and actomyosin suppress YAP1 export, and nuclear export is central to YAP1 regulation.
Cell Systems · Jun 1, 2018Peer-reviewedMolecular Biology