SMCHD1 activates the expression of genes required for the expansion of human myoblasts
Matthew Man-Kin Wong, Sarah Hachmer, Ed Gardner, Valeria Runfola, Eric Arezza, Lynn A Megeney, Charles P Emerson, Davide Gabellini, F Jeffrey Dilworth
This study shows SMCHD1 activates cell cycle genes in human myoblasts, promoting proliferation independently of DUX4, and identifies LAP2 as a key target gene.
bioRxiv · Feb 4, 2024Cell Biology