Author

Sarah Hachmer

University of Wisconsin SystemORCID 0009-0006-8777-7198Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Francis Jeffrey DilworthiD· 3 shared Eric ArezzaiD· 2 shared Lynn A. MegeneyiD· 2 shared Anand ParikhiD· 1 shared Anthony N. ImbalzanoiD· 1 shared Bassam AlbraidyiD· 1 shared Brian Daniel LarseniD· 1 shared Carmen G. PaliiiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Francis Jeffrey DilworthORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 21, 2026

Reciprocal regulation between the protein arginine deiminases and mSWI/SNF chromatin remodelers controls skeletal muscle differentiation and regeneration

Monserrat Olea‐Flores, Tapan Sharma, Anand Parikh…·Anthony N. Imbalzano

This study shows PADs and mSWI/SNF chromatin remodelers reciprocally regulate each other's expression and function in skeletal muscle differentiation and regeneration.

DOI 10.64898/2026.01.20.700682

mouseexperimental assay

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GenomicsbioRxivPreprintSep 24, 2024

Caspase-Activated DNase Localizes to Cancer Causing Translocation Breakpoints During Cell Differentiation

Dalal Alsowaida, Brian Daniel Larsen, Sarah Hachmer…·Lynn A. Megeney

The paper identifies CAD-bound genes involved in both muscle cell differentiation and cancer-causing translocations, showing CAD-induced breaks are physiologic in differentiation and linked to oncogenic gene regulation.

DOI 10.1101/2024.09.24.614809

mousehuman

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Cell BiologyNucleic Acids ResearchPeer-reviewedJun 27, 2024

SMCHD1 activates the expression of genes required for the expansion of human myoblasts

Matthew Man-Kin Wong, Sarah Hachmer, Ed Gardner…·Francis Jeffrey Dilworth

This study shows SMCHD1 activates cell cycle genes in human myoblasts, promoting proliferation independently of DUX4, and identifies LAP2 as a key target gene.

5 citations

humanDNA methylation

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