ImmunologybioRxivPreprint
Glycosylation-dependent modulation of the lL-2 signaling axis determines Th17 differentiation and IL-10 production
Leona Gabryšová, Elizabeth H. Mann, Lydia Bradley…·Anne O’Garra
This study shows that 2-deoxyglucose modulates IL-2 signaling to influence Th17 differentiation and IL-10 production by inhibiting glycosylation rather than glycolysis.
DOI 10.1101/287920